Effects of Suvorexant, an Orexin Receptor Antagonist, on Sleep Parameters as Measured by Polysomnography in Healthy Men | Zendy

Hong Sun | Zendy; William P. Kennedy | Zendy; Darren Wilbraham | Zendy; Nicole Lewis | Zendy; Nicole Calder | Zendy; Xiaodong Li | Zendy; Junshui Ma | Zendy; Ka Lai Yee | Zendy; Susan J. Ermlich | Zendy; Eric Mangin | Zendy; Christopher Lines | Zendy; Laura Rosen | Zendy; Jeffrey Chodakewitz | Zendy; Gail Murphy | Zendy

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Effects of Suvorexant, an Orexin Receptor Antagonist, on Sleep Parameters as Measured by Polysomnography in Healthy Men

Author(s) -

Hong Sun,

William P. Kennedy,

Darren Wilbraham,

Nicole Lewis,

Nicole Calder,

Xiaodong Li,

Junshui Ma,

Ka Lai Yee,

Susan J. Ermlich,

Eric Mangin,

Christopher Lines,

Laura Rosen,

Jeffrey Chodakewitz,

Gail Murphy

Publication year - 2013

Publication title -

sleep

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.222

H-Index - 207

eISSN - 1550-9109

pISSN - 0161-8105

DOI - 10.5665/sleep.2386

Subject(s) - polysomnography , orexin receptor , orexin , antagonist , insomnia , medicine , sleep (system call) , orexin a , anesthesia , psychology , psychiatry , receptor , apnea , neuropeptide , computer science , operating system

Suvorexant (MK-4305) is an orexin receptor antagonist being developed for the treatment of insomnia. This report describes the effects of nighttime administration of suvorexant on polysomnography (PSG) sleep parameters in healthy young men.

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