Open AccessHypocretin Deficiency Develops During Onset of Human Narcolepsy with Cataplexy
Author(s) -
Antri Savvidou,
Stine Knudsen,
Mia Olsson-Engman,
Steen Gammeltoft,
Poul Jennum,
Lars Palm
Publication year - 2012
Publication title -
sleep
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.222
H-Index - 207
eISSN - 1550-9109
pISSN - 0161-8105
DOI - 10.5665/sleep.2320
Subject(s) - narcolepsy , cataplexy , orexin , medicine , pediatrics , neurology , psychiatry , neuropeptide , receptor
Although hypothesized through animal studies, a temporal and causal association between hypocretin deficiency and the onset of narcolepsy with cataplexy (NC) has never been proven in humans.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom