Obstructive Sleep Apnea is Associated with Increased Chemoreflex Sensitivity in Patients with Metabolic Syndrome | Zendy

Ivani C. Trombetta | Zendy; Cristiane MakiNunes | Zendy; Edgar ToschiDias | Zendy; MariaJanieire N. N. Alves | Zendy; Maria Urbana Pinto Brandão Rondon | Zendy; Felipe X. Cepeda | Zendy; Luciano F. Drager | Zendy; Ana Braga | Zendy; Geraldo LorenziFilho | Zendy; Carlos Eduardo Negrão | Zendy

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Obstructive Sleep Apnea is Associated with Increased Chemoreflex Sensitivity in Patients with Metabolic Syndrome

Author(s) -

Ivani C. Trombetta,

Cristiane MakiNunes,

Edgar ToschiDias,

MariaJanieire N. N. Alves,

Maria Urbana Pinto Brandão Rondon,

Felipe X. Cepeda,

Luciano F. Drager,

Ana Braga,

Geraldo LorenziFilho,

Carlos Eduardo Negrão

Publication year - 2012

Publication title -

sleep

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.222

H-Index - 207

eISSN - 1550-9109

pISSN - 0161-8105

DOI - 10.5665/sleep.2298

Subject(s) - obstructive sleep apnea , metabolic syndrome , medicine , sleep apnea , apnea , sleep (system call) , cardiology , anesthesia , obesity , computer science , operating system

Obstructive sleep apnea (OSA) is often observed in patients with metabolic syndrome (MetS). In addition, the association of MetS and OSA substantially increases sympathetic nerve activity. However, the mechanisms involved in sympathetic hyperactivation in patients with MetS + OSA remain to be clarified. We tested the hypothesis that chemoreflex sensitivity is heightened in patients with MetS and OSA.

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