A Pathway-Based Analysis on the Effects of Obstructive Sleep Apnea in Modulating Visceral Fat Transcriptome | Zendy

Sina A. Gharib | Zendy; Amanda L. Hayes | Zendy; Michael J. Rosen | Zendy; Sanjay R. Patel | Zendy

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A Pathway-Based Analysis on the Effects of Obstructive Sleep Apnea in Modulating Visceral Fat Transcriptome

Author(s) -

Sina A. Gharib,

Amanda L. Hayes,

Michael J. Rosen,

Sanjay R. Patel

Publication year - 2012

Publication title -

sleep

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.222

H-Index - 207

eISSN - 1550-9109

pISSN - 0161-8105

DOI - 10.5665/sleep.2294

Subject(s) - obstructive sleep apnea , transcriptome , adipose tissue , medicine , bioinformatics , sleep apnea , gene expression profiling , hypoxia (environmental) , body mass index , endocrinology , biology , gene expression , gene , genetics , chemistry , organic chemistry , oxygen

Obstructive sleep apnea (OSA) has been associated with metabolic dysregulation and systemic inflammation. This may be due to pathophysiologic effects of OSA on visceral adipose tissue. We sought to assess the transcriptional consequences of OSA on adipocytes by utilizing pathway-focused analyses.

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