Repeated Melatonin Supplementation Improves Sleep in Hypertensive Patients Treated with Beta-Blockers: A Randomized Controlled Trial | Zendy

Frank A. J. L. Scheer | Zendy; Christopher J. Morris | Zendy; Joanna I. Garcia | Zendy; Carolina Smales | Zendy; Erin E. Kelly | Zendy; Jenny Marks | Zendy; Atul Malhotra | Zendy; Steven A. Shea | Zendy

Open Access

Repeated Melatonin Supplementation Improves Sleep in Hypertensive Patients Treated with Beta-Blockers: A Randomized Controlled Trial

Author(s) -

Frank A. J. L. Scheer,

Christopher J. Morris,

Joanna I. Garcia,

Carolina Smales,

Erin E. Kelly,

Jenny Marks,

Atul Malhotra,

Steven A. Shea

Publication year - 2012

Publication title -

sleep

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.222

H-Index - 207

eISSN - 1550-9109

pISSN - 0161-8105

DOI - 10.5665/sleep.2122

Subject(s) - melatonin , medicine , sleep onset latency , placebo , polysomnography , atenolol , discontinuation , randomized controlled trial , anesthesia , sleep onset , insomnia , blood pressure , pharmacology , alternative medicine , apnea , pathology

In the United States alone, approximately 22 million people take beta-blockers chronically. These medications suppress endogenous nighttime melatonin secretion, which may explain a reported side effect of insomnia. Therefore, we tested whether nightly melatonin supplementation improves sleep in hypertensive patients treated with beta-blockers.

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