Altered Sleep and Affect in the Neurotensin Receptor 1 Knockout Mouse
Author(s) -
Karrie Fitzpatrick,
Christopher J. Winrow,
Anthony L. Gotter,
Joshua Millstein,
Janna Arbuzova,
Joseph Brunner,
Andrew Kasarskis,
Martha Hotz Vitaterna,
John J. Renger,
Fred W. Turek
Publication year - 2012
Publication title -
sleep
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.222
H-Index - 207
eISSN - 1550-9109
pISSN - 0161-8105
DOI - 10.5665/sleep.1958
Subject(s) - affect (linguistics) , neurotensin , knockout mouse , sleep (system call) , endocrinology , receptor , neurotensin receptor , neuroscience , medicine , sleep deprivation , psychology , biology , circadian rhythm , neuropeptide , communication , computer science , operating system
Sleep and mood disorders have long been understood to have strong genetic components, and there is considerable comorbidity of sleep abnormalities and mood disorders, suggesting the involvement of common genetic pathways. Here, we examine a candidate gene implicated in the regulation of both sleep and affective behavior using a knockout mouse model.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom