Decoupling of Sleepiness from Sleep Time and Intensity during Chronic Sleep Restriction: Evidence for a Role of the Adenosine System | Zendy

Youngsoo Kim | Zendy; Yunren Bolortuya | Zendy; Lichao Chen | Zendy; Radhika Basheer | Zendy; Robert W. McCarley | Zendy; Robert E. Strecker | Zendy

Open Access

Decoupling of Sleepiness from Sleep Time and Intensity during Chronic Sleep Restriction: Evidence for a Role of the Adenosine System

Author(s) -

Youngsoo Kim,

Yunren Bolortuya,

Lichao Chen,

Radhika Basheer,

Robert W. McCarley,

Robert E. Strecker

Publication year - 2012

Publication title -

sleep

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.222

H-Index - 207

eISSN - 1550-9109

pISSN - 0161-8105

DOI - 10.5665/sleep.1890

Subject(s) - sleep deprivation , sleep restriction , basal forebrain , neurochemical , wakefulness , medicine , psychology , sleep (system call) , endocrinology , neuroscience of sleep , sleep debt , non rapid eye movement sleep , adenosine a2a receptor , neuroscience , adenosine receptor , circadian rhythm , electroencephalography , receptor , central nervous system , computer science , operating system , agonist

Sleep responses to chronic sleep restriction (CSR) might be very different from those observed after short-term total sleep deprivation. For example, after sleep restriction continues for several consecutive days, animals no longer express compensatory increases in daily sleep time and sleep intensity. However, it is unknown if these allostatic, or adaptive, sleep responses to CSR are paralleled by behavioral and neurochemical measures of sleepiness.

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