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A Closed Literature-Based Discovery Technique Finds a Mechanistic Link Between Hypogonadism and Diminished Sleep Quality in Aging Men
Author(s) -
Christopher M. Miller,
Thomas C. Rindflesch,
Marcelo Fiszman,
Dimitar Hristovski,
Dongwook Shin,
Graciela Rosemblat,
Han Zhang,
Kingman P. Strohl
Publication year - 2012
Publication title -
sleep
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.222
H-Index - 207
eISSN - 1550-9109
pISSN - 0161-8105
DOI - 10.5665/sleep.1640
Subject(s) - mechanism (biology) , sleep (system call) , testosterone (patch) , medline , association (psychology) , psychology , cognitive psychology , sleep deprivation , medicine , clinical psychology , bioinformatics , neuroscience , computer science , circadian rhythm , biology , psychotherapist , philosophy , biochemistry , epistemology , operating system
Sleep quality commonly diminishes with age, and, further, aging men often exhibit a wider range of sleep pathologies than women. We used a freely available, web-based discovery technique (Semantic MEDLINE) supported by semantic relationships to automatically extract information from MEDLINE titles and abstracts.

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