Open AccessCSF Levels of Hypocretin-1 (Orexin-A) Peak during Early Infancy in Humans
Author(s) -
Adi Aran,
Irina Shors,
Ling Lin,
Emmanuel Mignot,
Michael S. Schimmel
Publication year - 2012
Publication title -
sleep
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.222
H-Index - 207
eISSN - 1550-9109
pISSN - 0161-8105
DOI - 10.5665/sleep.1618
Subject(s) - orexin , medicine , cerebrospinal fluid , gestational age , neuropeptide , wakefulness , radioimmunoassay , orexin a , gestation , pediatrics , endocrinology , pregnancy , electroencephalography , biology , receptor , psychiatry , genetics
Hypocretin (orexin) is a unique neuropeptide involved in the consolidation of wakefulness and sleep. Although hypocretin-1 levels in the cerebrospinal fluid (CSF) are stable after infancy, how levels change in preterm and term human infants is unknown.
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