Stimulus-Induced, Sleep-Bound, Focal Seizures: A Case Report
Author(s) -
Francesca Siclari,
Lino Nobili,
Giorgio Lo Russo,
Alessio Moscato,
Alfred Buck,
Claudio L. Bassetti,
Ramin Khatami
Publication year - 2011
Publication title -
sleep
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.222
H-Index - 207
eISSN - 1550-9109
pISSN - 0161-8105
DOI - 10.5665/sleep.1448
Subject(s) - stimulus (psychology) , psychology , audiology , electroencephalography , sleep (system call) , neuroscience , medicine , cognitive psychology , computer science , operating system
In nocturnal frontal lobe epilepsy (NFLE), seizures occur almost exclusively during NREM sleep. Why precisely these seizures are sleep-bound remains unknown. Studies of patients with nonlesional familial forms of NFLE have suggested the arousal system may play a major role in their pathogenesis. We report the case of a patient with pharmaco-resistant, probably cryptogenic form of non-familial NFLE and strictly sleep-bound seizures that could be elicited by alerting stimuli and were associated with ictal bilateral thalamic and right orbital-insular hyperperfusion on SPECT imaging.
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