Shared Genetic Background for Regulation of Mood and Sleep: Association of GRIA3 with Sleep Duration in Healthy Finnish Women | Zendy

Siddheshwar Utge | Zendy; Erkki Kronholm | Zendy; Timo Partonen | Zendy; Pia Soronen | Zendy; Hanna M. Ollila | Zendy; Anu Loukola | Zendy; Markus Perola | Zendy; Veikko Salomaa | Zendy; Tarja PorkkaHeiskanen | Zendy; Tiina Paunio | Zendy

Open Access

Shared Genetic Background for Regulation of Mood and Sleep: Association of GRIA3 with Sleep Duration in Healthy Finnish Women

Author(s) -

Siddheshwar Utge,

Erkki Kronholm,

Timo Partonen,

Pia Soronen,

Hanna M. Ollila,

Anu Loukola,

Markus Perola,

Veikko Salomaa,

Tarja PorkkaHeiskanen,

Tiina Paunio

Publication year - 2011

Publication title -

sleep

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.222

H-Index - 207

eISSN - 1550-9109

pISSN - 0161-8105

DOI - 10.5665/sleep.1268

Subject(s) - sleep (system call) , mood , major depressive disorder , sleep debt , association (psychology) , psychology , psychiatry , delayed sleep phase , insomnia , medicine , sleep disorder , risk factor , computer science , operating system , psychotherapist

Sleeping 7 to 8 hours per night appears to be optimal, since both shorter and longer sleep times are related to increased morbidity and mortality. Depressive disorder is almost invariably accompanied by disturbed sleep, leading to decreased sleep duration, and disturbed sleep may be a precipitating factor in the initiation of depressive illness. Here, we examined whether, in healthy individuals, sleep duration is associated with genes that we earlier found to be associated with depressive disorder.

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