Effects of Sleep Apnea on Nocturnal Free Fatty Acids in Subjects with Heart Failure | Zendy

Jonathan C. Jun | Zendy; Luciano F. Drager | Zendy; Samer S. Najjar | Zendy; Stephen S. Gottlieb | Zendy; Cynthia D. Brown | Zendy; Philip L. Smith | Zendy; Alan R. Schwartz | Zendy; Vsevolod Y. Polotsky | Zendy

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Effects of Sleep Apnea on Nocturnal Free Fatty Acids in Subjects with Heart Failure

Author(s) -

Jonathan C. Jun,

Luciano F. Drager,

Samer S. Najjar,

Stephen S. Gottlieb,

Cynthia D. Brown,

Philip L. Smith,

Alan R. Schwartz,

Vsevolod Y. Polotsky

Publication year - 2011

Publication title -

sleep

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.222

H-Index - 207

eISSN - 1550-9109

pISSN - 0161-8105

DOI - 10.5665/sleep.1240

Subject(s) - heart failure , medicine , sleep apnea , apnea , hypoxemia , central sleep apnea , intermittent hypoxia , hypoxia (environmental) , ejection fraction , cardiology , obstructive sleep apnea , hypopnea , endocrinology , polysomnography , anesthesia , oxygen , chemistry , organic chemistry

Sleep apnea is common in patients with congestive heart failure, and may contribute to the progression of underlying heart disease. Cardiovascular and metabolic complications of sleep apnea have been attributed to intermittent hypoxia. Elevated free fatty acids (FFA) are also associated with the progression of metabolic, vascular, and cardiac dysfunction. The objective of this study was to determine the effect of intermittent hypoxia on FFA levels during sleep in patients with heart failure.

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