Tissue Oxygenation in Brain, Muscle, and Fat in a Rat Model of Sleep Apnea: Differential Effect of Obstructive Apneas and Intermittent Hypoxia
Author(s) -
Isaac Almendros,
Ramón Farré,
Anna M. Planas,
Marta Torres,
Maria R. Bonsignore,
Daniel Navajas,
Josep M. Montserrat
Publication year - 2011
Publication title -
sleep
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.222
H-Index - 207
eISSN - 1550-9109
pISSN - 0161-8105
DOI - 10.5665/sleep.1176
Subject(s) - intermittent hypoxia , obstructive sleep apnea , hypoxia (environmental) , medicine , cerebral cortex , anesthesia , oxygenation , apnea , endocrinology , lipid peroxidation , oxidative stress , cerebral hypoxia , chemistry , ischemia , oxygen , organic chemistry
To test the hypotheses that the dynamic changes in brain oxygen partial pressure (PtO(2)) in response to obstructive apneas or to intermittent hypoxia differ from those in other organs and that the changes in brain PtO(2) in response to obstructive apneas is a source of oxidative stress.
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