Upper Airway Genioglossal Activity in Children with Sickle Cell Disease | Zendy

Jingtao Huang | Zendy; Swaroop Pinto | Zendy; Julian L. Allen | Zendy; Raanan Arens | Zendy; Cheryl Y. Bowdre | Zendy; Abbas F. Jawad | Zendy; Thornton B.A. Mason | Zendy; Kwaku OheneFrempong | Zendy; Kim SmithWhitley | Zendy; Carole L. Marcus | Zendy

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Upper Airway Genioglossal Activity in Children with Sickle Cell Disease

Author(s) -

Jingtao Huang,

Swaroop Pinto,

Julian L. Allen,

Raanan Arens,

Cheryl Y. Bowdre,

Abbas F. Jawad,

Thornton B.A. Mason,

Kwaku OheneFrempong,

Kim SmithWhitley,

Carole L. Marcus

Publication year - 2011

Publication title -

sleep

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.222

H-Index - 207

eISSN - 1550-9109

pISSN - 0161-8105

DOI - 10.5665/sleep.1046

Subject(s) - medicine , obstructive sleep apnea , continuous positive airway pressure , airway , anesthesia , apnea , tonicity , population , cardiology , gastroenterology , environmental health

The prevalence of obstructive sleep apnea syndrome (OSAS) in sickle cell disease (SCD) has been reported to be higher than that in the general pediatric population. However, not all subjects with SCD develop OSAS. We hypothesized that SCD patients with OSAS have a blunted neuromuscular response to subatmospheric pressure loads during sleep, making them more likely to develop upper airway collapse.

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