Associations Between the Apnea-Hypopnea Index During REM and NREM Sleep and Cognitive Functioning in a Cohort of Middle-Aged Adults | Zendy

Maria Devita | Zendy; Paul E. Peppard | Zendy; Arthur Eumann Mesas | Zendy; Sara Mondini | Zendy; Maria Luisa Rusconi | Zendy; Jodi H. Barnet | Zendy; Erika W. Hagen | Zendy

Open Access

Associations Between the Apnea-Hypopnea Index During REM and NREM Sleep and Cognitive Functioning in a Cohort of Middle-Aged Adults

Author(s) -

Maria Devita,

Paul E. Peppard,

Arthur Eumann Mesas,

Sara Mondini,

Maria Luisa Rusconi,

Jodi H. Barnet,

Erika W. Hagen

Publication year - 2019

Publication title -

journal of clinical sleep medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.529

H-Index - 92

eISSN - 1550-9397

pISSN - 1550-9389

DOI - 10.5664/jcsm.7872

Subject(s) - non rapid eye movement sleep , polysomnography , medicine , audiology , effects of sleep deprivation on cognitive performance , psychomotor vigilance task , cognition , obstructive sleep apnea , cohort , apnea–hypopnea index , psychology , anesthesia , psychiatry , sleep deprivation , apnea , electroencephalography

Prior research has linked obstructive sleep apnea (OSA) to varied cognitive deficits. Additionally, OSA in rapid eye movement (REM) versus non-rapid eye movement (NREM) sleep has been shown to be a stronger predictor of outcomes such as hypertension. The present study aimed to investigate whether OSA-as characterized by the apnea-hypopnea index (AHI)-during REM and NREM sleep is associated with performance on a range of cognitive tasks. We also investigated whether the presence/absence of the apolipoprotein E4 allele (APOE4) modifies the associations between AHI during REM and NREM sleep and cognitive performance.

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