Two Cases of Sleep-Related Eating Disorder Responding Promptly to Low-Dose Sertraline Therapy | Zendy

Ranji Varghese | Zendy; Jorge Rey de Castro | Zendy; César Liendo | Zendy; Carlos H. Schenck | Zendy

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Two Cases of Sleep-Related Eating Disorder Responding Promptly to Low-Dose Sertraline Therapy

Author(s) -

Ranji Varghese,

Jorge Rey de Castro,

César Liendo,

Carlos H. Schenck

Publication year - 2018

Publication title -

journal of clinical sleep medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.529

H-Index - 92

eISSN - 1550-9397

pISSN - 1550-9389

DOI - 10.5664/jcsm.7404

Subject(s) - sertraline , medicine , bedtime , sleepwalking , psychiatry , fluvoxamine , parasomnia , sleep disorder , insomnia , antidepressant , fluoxetine , anxiety , receptor , serotonin

We report two cases of adult males with sleep-related eating disorder (SRED), with durations of 3 and 7 years, and without associated psychiatric history. In both cases, the use of low-dose (25 mg) sertraline taken at bedtime resulted in immediate, full and sustained resolution of symptoms at the latest follow-ups. The sertraline efficacy was of particular benefit for the patient reported on in case 2 who was a commercial airline pilot subjected to a highly restricted list of Federal Aviation Administration-approved medications. Risk factors for SRED included smoking cessation and work-related stress in case 1, and a history of sleepwalking and work-related circadian disruptions and partial sleep deprivations in case 2. Sertraline therapy of SRED is considered within a review of all current pharmacologic therapies of SRED.

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