Randomized Controlled Trial of Melatonin for Sleep Disturbance in Dravet Syndrome: The DREAMS Study | Zendy

Kenneth A. Myers | Zendy; Margot J. Davey | Zendy; Michael S. Ching | Zendy; Colin A. Ellis | Zendy; Bronwyn E. Grinton | Zendy; Annie Roten | Zendy; Paul Lightfoot | Zendy; Ingrid E. Scheffer | Zendy

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Randomized Controlled Trial of Melatonin for Sleep Disturbance in Dravet Syndrome: The DREAMS Study

Author(s) -

Kenneth A. Myers,

Margot J. Davey,

Michael S. Ching,

Colin A. Ellis,

Bronwyn E. Grinton,

Annie Roten,

Paul Lightfoot,

Ingrid E. Scheffer

Publication year - 2018

Publication title -

journal of clinical sleep medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.529

H-Index - 92

eISSN - 1550-9397

pISSN - 1550-9389

DOI - 10.5664/jcsm.7376

Subject(s) - dravet syndrome , actigraphy , melatonin , medicine , sleep disorder , sleep onset , randomized controlled trial , epilepsy , pittsburgh sleep quality index , placebo , pramipexole , pediatrics , anesthesia , insomnia , psychiatry , alternative medicine , disease , pathology , parkinson's disease , sleep quality

Dravet syndrome is a severe developmental and epileptic encephalopathy, in which 75% of patients have sleep disturbance. Melatonin is often used for sleep problems in childhood; however, there is no quality evidence supporting its use in Dravet syndrome. We hypothesized that melatonin would increase total sleep and quality of life for patients with Dravet syndrome.

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