CPAP Therapy Delays Cardiovagal Reactivation and Decreases Arterial Renin-Angiotensin System Activity in Humans With Obstructive Sleep Apnea | Zendy

David D. M. Nicholl | Zendy; Patrick J. Hanly | Zendy; Ann A. Zalucky | Zendy; Michelle Mann | Zendy; Jennifer M. MacRae | Zendy; Marc J. Poulin | Zendy; George B. Handley | Zendy; Darlene Y. Sola | Zendy; Sofia B. Ahmed | Zendy

Open Access

CPAP Therapy Delays Cardiovagal Reactivation and Decreases Arterial Renin-Angiotensin System Activity in Humans With Obstructive Sleep Apnea

Author(s) -

David D. M. Nicholl,

Patrick J. Hanly,

Ann A. Zalucky,

Michelle Mann,

Jennifer M. MacRae,

Marc J. Poulin,

George B. Handley,

Darlene Y. Sola,

Sofia B. Ahmed

Publication year - 2018

Publication title -

journal of clinical sleep medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.529

H-Index - 92

eISSN - 1550-9397

pISSN - 1550-9389

DOI - 10.5664/jcsm.7326

Subject(s) - medicine , obstructive sleep apnea , renin–angiotensin system , cardiology , sleep (system call) , continuous positive airway pressure , sleep apnea , apnea , blood pressure , anesthesia , computer science , operating system

Obstructive sleep apnea (OSA) is associated with increased cardiovascular risk. The effect of OSA treatment with continuous positive airway pressure (CPAP) on the cardiovascular response to a stressor is unknown. We sought to determine the effect of CPAP therapy on heart rate variability (HRV) and arterial stiffness, at baseline, in response to, and recovery from a physiological stressor, Angiotensin II (AngII), in humans with OSA.

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