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Evolution of Obstructive Sleep Apnea in Infants with Cleft Palate and Micrognathia
Author(s) -
Christopher M. Cielo︎,
Jesse A. Taylor,
Arastoo Vossough,
Jerilynn Radcliffe,
Allison Thomas,
Ruth Bradford,
Janet Lioy,
Ignacio E. Tapia,
Reza Assadsangabi,
Justine Shults,
Carole L. Marcus
Publication year - 2016
Publication title -
journal of clinical sleep medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.529
H-Index - 92
eISSN - 1550-9397
pISSN - 1550-9389
DOI - 10.5664/jcsm.5930
Subject(s) - medicine , obstructive sleep apnea , craniofacial , polysomnography , hypoplasia , cohort , cephalometry , pediatrics , prospective cohort study , craniofacial abnormality , apnea , orthodontics , psychiatry
Children with craniofacial anomalies are a heterogeneous group at high risk for obstructive sleep apnea (OSA). However, the prevalence and structural predictors of OSA in this population are unknown. We hypothesized that infants with micrognathia would have more significant OSA than those with isolated cleft palate ± cleft lip (ICP), and those with ICP would have more significant OSA than controls. We postulated that OSA severity would correlate with reduced mandibular size, neurodevelopmental scores, and growth.

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