The Effect of Two Benzodiazepine Receptor Agonist Hypnotics on Sleep-Dependent Memory Consolidation | Zendy

Janine M. Hall-Porter | Zendy; Paula K. Schweitzer | Zendy; Rhody D. Eisenstein | Zendy; Hasan Ali H. Ahmed | Zendy; James K. Walsh | Zendy

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The Effect of Two Benzodiazepine Receptor Agonist Hypnotics on Sleep-Dependent Memory Consolidation

Author(s) -

Janine M. Hall-Porter,

Paula K. Schweitzer,

Rhody D. Eisenstein,

Hasan Ali H. Ahmed,

James K. Walsh

Publication year - 2014

Publication title -

journal of clinical sleep medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.529

H-Index - 92

eISSN - 1550-9397

pISSN - 1550-9389

DOI - 10.5664/jcsm.3352

Subject(s) - medicine , sleep medicine , sleep (system call) , sleep disorder , psychiatry , insomnia , computer science , operating system

Numerous studies have demonstrated that sleep promotes memory consolidation, but there is little research on the effect of hypnotics on sleep-dependent memory consolidation. We compared bedtime administration of zolpidem-ER 12.5 mg (6- to 8-h duration of action), middle-of-the-night administration of zaleplon 10 mg (3- to 4-h duration of action), and placebo to examine the effect of different durations of hypnotic drug exposure on memory consolidation during sleep.

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