Open AccessImprovement of Restless Legs Syndrome by Varenicline as Antismoking Treatment
Author(s) -
Andrea Romigi,
Giuseppe Vitrani
Publication year - 2013
Publication title -
journal of clinical sleep medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.529
H-Index - 92
eISSN - 1550-9397
pISSN - 1550-9389
DOI - 10.5664/jcsm.3092
Subject(s) - varenicline , restless legs syndrome , medicine , partial agonist , smoking cessation , pharmacotherapy , agonist , nicotinic agonist , pharmacology , insomnia , receptor , pathology
Varenicline is a partial agonist at the α4β2 nicotinic acetylcholine receptor effective as smoking cessation pharmacotherapy. We present a familial case of severe restless legs syndrome (RLS) resistant to polytherapy who showed a consistent and effective amelioration of RLS symptoms after introduction of varenicline as antismoking drug.
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