THE INFLUENCE OF METABOLIC SYNDROME ON T HE QUALITY OF LIFE IN PATIENTS WITH ACU TE MYOCARDIAL INFARCTION WITH ST SEGMENT ELEVATION

Metabolic syndrome (MetS) is a cluster of several risk factors that may indicate worse outcome after myocardial infarction with ST segment elevation (STEMI). The aim of this study was to determine the impact of MetS on quality of life among patients with STEMI. A prospective study was performed among all STEMI patients who were treated with primary percutaneous coronary intervention in Clinical Centre of Serbia. During the three-year follow up, the occurrence of new cardiovascular events was followed. After 36 months the valid data were collected for 507 patients. At the end of the follow up, all alive and capable patients completed the Short Form 36 (SF-36) questionnaire. The prevalence of MetS was 42.80%. An increased appearance of new myocardial infarction (p = 0.004), new unexpected revascularizations (p = 0.014) and the increased number of hospitalizations because of heart failure (p = 0.050) were recorded in the group of patients with MetS during a follow-up. Multiple regression analysis revealed that MetS was a predictor for lower scores of: physical functioning (OR 2.684; p < 0.001), role physical functioning (OR 2.121; p = 0.001), bodily pain (OR 2.559; p = 0.005), general health (OR 2.522; p < 0.001) and physical component score (OR 2.516; p < 0.001). Among mental components, MetS was a predictor of lower scores of vitality (OR 1.999; p = 0.002) and mental health (OR 2.142; p = 0.016). Patients with MetS are at high risk for the appearance of new cardiovascular events, and the presence of this syndrome is associated with poorer quality of life after surviving STEMI. Acta Medica Medianae 2018;57(4):71-78.