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CLOSTRIDIUM DIFFICILE COLITIS - A ROLE OF SURGERY
Author(s) -
Ladislav Mitáš,
Tomáš Skřička,
Zdeněk Kala,
Pavel Polák,
Igor Penka,
Markéta Hanslianová,
Beáta Hemmelová
Publication year - 2015
Publication title -
acta medica medianae
Language(s) - English
Resource type - Journals
eISSN - 1821-2794
pISSN - 0365-4478
DOI - 10.5633/amm.2015.0113
Subject(s) - medicine , ileostomy , clostridium difficile , fulminant , clostridium difficile colitis , colitis , colectomy , surgery , clostridium , antibiotics , general surgery , gastroenterology , disease , ulcerative colitis , microbiology and biotechnology , bacteria , biology , genetics
Clostridium difficile infection (CDI) is the most frequent cause of nococomial diarrhoea. Most cases are succesfully treated by antibiotic therapy, but nearly 10% may progress to the fulminant form. The aim of this work is a retrospective evaluation of the results of surgical treatment of patients with the severe Costridium colitis, in the period 2008-2014. Clostridium toxins were detected in patients in Bohunice University Hospital in 1956. Thirty seven of them underwent surgery due to toxic colitis. There were 6 total colectomies with terminal ileostomy, 29 subtotal colectomies with terminal ileostomy, 1 coecostomy and 1 axial ileostomy. The 30-day mortality was nearly 35 %, 90- day mortality 54% and morbidity 89%. Early and precise indication for surgery could save about 65% of patients with fulminant course of Clostridium difficile colitis

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