Assessment of the influence of peripheral blood mononuclear cell stimulation with Streptococcus pneumoniae polysaccharides on expression of selected Toll-like receptors, activation markers and Fas antigen in patients with chronic lymphocytic leukemia | Zendy

Ewelina Grywalska | Zendy; Anna Hymos | Zendy; Izabela KoronaGłowniak | Zendy; Marcin Pasiarski | Zendy; Agnieszka Stelmach-Gołdyś | Zendy; Stanisław Góźdż | Zendy; Anna Malm | Zendy; Jacek Roliński | Zendy

Open Access

Assessment of the influence of peripheral blood mononuclear cell stimulation with Streptococcus pneumoniae polysaccharides on expression of selected Toll-like receptors, activation markers and Fas antigen in patients with chronic lymphocytic leukemia

Author(s) -

Ewelina Grywalska,

Anna Hymos,

Izabela KoronaGłowniak,

Marcin Pasiarski,

Agnieszka Stelmach-Gołdyś,

Stanisław Góźdż,

Anna Malm,

Jacek Roliński

Publication year - 2016

Publication title -

postępy higieny i medycyny doświadczalnej

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.275

H-Index - 34

eISSN - 1732-2693

pISSN - 0032-5449

DOI - 10.5604/17322693.1219399

Subject(s) - peripheral blood mononuclear cell , cd19 , antigen , chronic lymphocytic leukemia , stimulation , pneumococcal polysaccharide vaccine , immunology , streptococcus pneumoniae , leukemia , medicine , biology , in vitro , microbiology and biotechnology , biochemistry , pneumococcal disease , antibiotics

Since 2012, both the 13-valent pneumococcal conjugate vaccine (PCV13) and the 23-valent pneumococcal polysaccharide vaccine (PPV23) have been recommended for pneumococcal infection prevention in patients with chronic lymphocytic leukemia (CLL). Available literature data indicate that leukemic cells may respond to the presence of pathogens through specific Toll-like receptors (TLR).

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