Wegener’s granulomatosis and pyoderma gangrenosum – rare causes of facial ulcerations | Zendy

Karolina Kędzierska | Zendy; Krzysztof Sindrewicz | Zendy; Tomasz Smektała | Zendy; Magda Wiśniewska | Zendy; Marek Masiuk | Zendy; Ewelina Staniszewska | Zendy; Katarzyna Sporniak–Tutak | Zendy; Edyta Gołembiewska | Zendy; Kazimierz Ciechanowski | Zendy

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Wegener’s granulomatosis and pyoderma gangrenosum – rare causes of facial ulcerations

Author(s) -

Karolina Kędzierska,

Krzysztof Sindrewicz,

Tomasz Smektała,

Magda Wiśniewska,

Marek Masiuk,

Ewelina Staniszewska,

Katarzyna Sporniak–Tutak,

Edyta Gołembiewska,

Kazimierz Ciechanowski

Publication year - 2016

Publication title -

postępy higieny i medycyny doświadczalnej

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.275

H-Index - 34

eISSN - 1732-2693

pISSN - 0032-5449

DOI - 10.5604/17322693.1197372

Subject(s) - pyoderma gangrenosum , medicine , dermatology , histopathology , immunosuppression , plasmapheresis , surgery , pathology , disease , immunology , antibody

Pyoderma gangrenosum (PG) is caused by immune system dysfunction, and particularly improper functioning of neutrophils. At least half of all PG patients also suffer from autoimmunological diseases, one of which is Wegener granulomatosis (WG). The purpose of this article was to compare cases of patients with WG and PG in terms of their clinical course, histopathology, and applied treatment. In both, histopathological features are not fully distinct. Data from microbiological and immunological evaluation and clinical presentation are required to establish the diagnosis. We also present the case of a patient with WG and deep facial skin lesions not responding to standard treatment.

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