Association and family studies of DRD2 gene polymorphisms in alcohol dependence syndrome | Zendy

Iwona Małecka | Zendy; A Jasiewicz | Zendy; Aleksandra Suchanecka | Zendy; Jerzy Samochowiec | Zendy; Anna Grzywacz | Zendy

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Association and family studies of DRD2 gene polymorphisms in alcohol dependence syndrome

Author(s) -

Iwona Małecka,

A Jasiewicz,

Aleksandra Suchanecka,

Jerzy Samochowiec,

Anna Grzywacz

Publication year - 2014

Publication title -

postępy higieny i medycyny doświadczalnej

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.275

H-Index - 34

eISSN - 1732-2693

pISSN - 0032-5449

DOI - 10.5604/17322693.1127883

Subject(s) - transmission disequilibrium test , alcohol dependence , allele , genetics , gene , single nucleotide polymorphism , genetic association , dopamine receptor , polymorphism (computer science) , pathogenesis , medicine , alcohol , biology , haplotype , genotype , receptor , biochemistry

The human dopamine receptor 2 gene DRD2 plays a central role in susceptibility to Alcohol Dependence Syndrome (ADS). The aim of this study was to evaluate 3 single nucleotide polymorphisms: D2 (rs1076560), Tag1D (rs1800498), Tag1B (rs1079597) located in dopamine receptor 2 DRD2 gene and its role in alcohol dependence.

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