Prevalence of Helicobacter pylori cagA, vacA, iceA, babA2 genotypes in Polish children and adolescents with gastroduodenal disease | Zendy

Monika Biernat | Zendy; Grażyna Gościniak | Zendy; Barbara Iwańczak | Zendy

Open Access

Prevalence of Helicobacter pylori cagA, vacA, iceA, babA2 genotypes in Polish children and adolescents with gastroduodenal disease

Author(s) -

Monika Biernat,

Grażyna Gościniak,

Barbara Iwańczak

Publication year - 2014

Publication title -

postępy higieny i medycyny doświadczalnej

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.275

H-Index - 34

eISSN - 1732-2693

pISSN - 0032-5449

DOI - 10.5604/17322693.1118211

Subject(s) - caga , helicobacter pylori , genotype , gastroenterology , gastritis , medicine , gerd , virulence , allele , disease , chronic gastritis , reflux , gene , biology , genetics

Infection with Helicobacter pylori is a major cause of chronic gastritis and peptic ulcer disease in children and its consequences in adulthood can lead to serious complications, including in particular the development of gastric cancer. Our aim was to analyze the relationship between the occurrence of selected genes such as cagA, vacA, iceA, and babA2 determining pathogenicity of H. pylori strains and clinical outcome in children.

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