Antimicrobial/anti-biofilm activity of expired blood platelets and their released products
Author(s) -
M. Różalski,
Bartłomiej Micota,
Beata Sadowska,
Małgorzata Paszkiewicz,
Marzena Więckowska-Szakiel,
Barbara Różalska
Publication year - 2013
Publication title -
postępy higieny i medycyny doświadczalnej
Language(s) - English
Resource type - Journals
eISSN - 1732-2693
pISSN - 0032-5449
DOI - 10.5604/17322693.1046009
Subject(s) - biofilm , platelet , antimicrobial , microbiology and biotechnology , staphylococcus aureus , vancomycin , linezolid , antibiotics , chemistry , platelet activation , bacteria , biology , immunology , genetics
Although platelets are not part of the classical immune system, they have many features that indicate their role in the anti-infective host defense. They come into interactions with microorganisms, which results in co-aggregation and co-adhesion or destruction of the microbes due to the action of antimicrobial peptides released from platelets.The aim of this study was to evaluate the killing effect of platelets against planktonic and biofilm cultures of Staphylococcus aureus and to test their synergy with antibiotics.
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