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Modified methods for efficiently differentiating human embryonic stem cells into chondrocyte-like cells
Author(s) -
Wiktoria Maria Suchorska,
Ewelina Augustyniak,
Magdalena Richter,
Magdalena Łukjanow,
Violetta Filas,
Jacek Kaczmarczyk,
Tomasz Trzeciak
Publication year - 2017
Publication title -
postępy higieny i medycyny doświadczalnej
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.275
H-Index - 34
eISSN - 1732-2693
pISSN - 0032-5449
DOI - 10.5604/01.3001.0010.3831
Subject(s) - chondrogenesis , embryonic stem cell , osteoarthritis , cartilage , chondrocyte , regeneration (biology) , stem cell , microbiology and biotechnology , tissue engineering , articular cartilage , stem cell transplantation for articular cartilage repair , biology , anatomy , pathology , medicine , adult stem cell , biomedical engineering , biochemistry , alternative medicine , gene
Human articular cartilage has a poor regenerative capacity. This often results in the serious joint disease- osteoarthritis (OA) that is characterized by cartilage degradation. An inability to self-repair provided extensive studies on AC regeneration. The cell-based cartilage tissue engineering is a promising approach for cartilage regeneration. So far, numerous cell types have been reported to show chondrogenic potential, among others human embryonic stem cells (hESCs).

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