Reliability of histopathological examination and immunohistochemistry of a single biopsy for evaluation of endometrial health in Icelandic mares | Zendy

Monika Sikora | Zendy; Marcin Nowak | Zendy; Henryk Racheniuk | Zendy; Katarzyna Wojtysiak | Zendy; Roland Kozdrowski | Zendy

Open Access

Reliability of histopathological examination and immunohistochemistry of a single biopsy for evaluation of endometrial health in Icelandic mares

Author(s) -

Monika Sikora,

Marcin Nowak,

Henryk Racheniuk,

Katarzyna Wojtysiak,

Roland Kozdrowski

Publication year - 2017

Publication title -

folia histochemica et cytobiologica

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.384

H-Index - 40

eISSN - 1897-5631

pISSN - 0239-8508

DOI - 10.5603/fhc.a2017.0017

Subject(s) - endometritis , biopsy , endometrial biopsy , infertility , medicine , immunohistochemistry , histopathology , gynecology , pathology , biology , pregnancy , genetics

Endometritis and endometrosis have been and still are the major reasons for infertility in mares. The diagnosis of endometritis can be based on cytology and microbiology, but endometrial biopsy is still the only way to diagnose endometrosis in the mare. Our study attempted to determine if a single biopsy using his-topathology and immunohistochemistry is sufficient to ascertain reasons for infertility in Icelandic mares. The objectives of this study were to examine the relationship between deviations in endometrial biopsies in terms of prostaglandin-endoperoxide synthase-2 (PTGS-2) and fibronectin expression and polymorphonuclear cells (PMNs) infiltration, as well as scoring degeneration in two endometrial biopsies.

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