Inhibition of EGFR nuclear shuttling decreases irradiation resistance in HeLa cells | Zendy

Hong Wei | Zendy; Zijie Zhu | Zendy; Longtao Lu | Zendy

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Inhibition of EGFR nuclear shuttling decreases irradiation resistance in HeLa cells

Author(s) -

Hong Wei,

Zijie Zhu,

Longtao Lu

Publication year - 2017

Publication title -

folia histochemica et cytobiologica

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.384

H-Index - 40

eISSN - 1897-5631

pISSN - 0239-8508

DOI - 10.5603/fhc.a2017.0007

Subject(s) - hela , nuclear localization sequence , carcinogenesis , viability assay , cancer research , cell , microbiology and biotechnology , nls , cell cycle , cell cycle checkpoint , programmed cell death , chemistry , biology , cancer , apoptosis , biochemistry , genetics , cytoplasm

Cervical cancer is a leading cause of mortality in women worldwide. The resistance to irradiation at the advanced stage is the main reason for the poor prognosis and high mortality. This work aims to elucidate the molecular mechanism underlying the radio-resistance.

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