Myenteric plexuses atrophy in the vicinity of colorectal cancer tissue is not caused by apoptosis or necrosis | Zendy

Anna Kozłowska | Zendy; Przemysław Kwiatkowski | Zendy; Agnieszka Oponowicz | Zendy; Mariusz Majewski | Zendy; Zbigniew Kmieć | Zendy; Janusz Godlewski | Zendy

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Myenteric plexuses atrophy in the vicinity of colorectal cancer tissue is not caused by apoptosis or necrosis

Author(s) -

Anna Kozłowska,

Przemysław Kwiatkowski,

Agnieszka Oponowicz,

Mariusz Majewski,

Zbigniew Kmieć,

Janusz Godlewski

Publication year - 2015

Publication title -

folia histochemica et cytobiologica

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.384

H-Index - 40

eISSN - 1897-5631

pISSN - 0239-8508

DOI - 10.5603/fhc.a2016.0012

Subject(s) - myenteric plexus , pathology , enteric nervous system , colorectal cancer , biology , large intestine , atrophy , cancer , immunohistochemistry , medicine , neuroscience , biochemistry , genetics

The previously performed studies showed that the presence of colorectal cancer (CRC) tumor is associated with the atrophy of myenteric plexuses in the vicinity of cancer invasion; however, the possible mechanisms of this phenomenon are not known. The aim of the present study was to determine whether the atrophic changes of the enteric nervous system (ENS) within an intestine wall of the CRC patients were caused by apoptosis or necrosis and whether they were associated with changes in the number of galanin-immunore-active (GAL-Ir) neurons.

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