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The influence of anti-TNF therapy on CD31 and VEGF expression in colonic mucosa of Crohn’s disease patients in relation to mucosal healing
Author(s) -
Piotr Eder,
Liliana ŁykowskaSzuber,
Katarzyna Iwanik,
Iwona KrelaKaźmierczak,
Kamila StawczykEder,
Przemysław Majewski,
Krzysztof Linke,
Elaine W. Kay,
Aldona Woźniak
Publication year - 2015
Publication title -
folia histochemica et cytobiologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.384
H-Index - 40
eISSN - 1897-5631
pISSN - 0239-8508
DOI - 10.5603/fhc.a2016.0008
Subject(s) - cd31 , angiogenesis , lamina propria , medicine , immunohistochemistry , pathogenesis , vascular endothelial growth factor , tumor necrosis factor alpha , crohn's disease , pathology , argon plasma coagulation , intestinal mucosa , gastroenterology , disease , vegf receptors , endoscopy , epithelium
Immune-mediated angiogenesis may play an important role in the pathogenesis of inflammatory lesions in Crohn's disease (CD). The study aimed to assess the influence of anti-tumour necrosis factor (anti-TNF) therapy on the angiogenesis in relation to microscopic and endoscopic healing in CD patients.

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