Changes of memory B- and T-cell subsets in lupus nephritis patients
Author(s) -
Joanna Kosałka-Węgiel,
Bogdan Jakieła,
Jacek Musiał
Publication year - 2015
Publication title -
folia histochemica et cytobiologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.384
H-Index - 40
eISSN - 1897-5631
pISSN - 0239-8508
DOI - 10.5603/fhc.a2016.0005
Subject(s) - immunoglobulin d , immunology , lupus nephritis , systemic lupus erythematosus , b cell , memory b cell , immune system , t cell , b 1 cell , memory t cell , naive b cell , biology , antibody , chemistry , medicine , antigen presenting cell , disease
Renal involvement in systemic lupus erythematosus (SLE) is associated with production of antibodies to double stranded DNA, deposition of immune complexes and organ damage. These processes have been linked with abnormalities in B- and T-cell memory compartments. The aim of the study was to analyze subsets of peripheral memory B-cells and T-cells in lupus nephritis (LN) patients.
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