Application of FISH method for preimplantation genetic diagnostics of reciprocal and Robertsonian translocations | Zendy

Joanna Liss | Zendy; Jolanta Kiewisz | Zendy; Judyta Zabielska | Zendy; Patrycja Kulwikowska | Zendy; Krzysztof Łukaszuk | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Application of FISH method for preimplantation genetic diagnostics of reciprocal and Robertsonian translocations

Author(s) -

Joanna Liss,

Jolanta Kiewisz,

Judyta Zabielska,

Patrycja Kulwikowska,

Krzysztof Łukaszuk

Publication year - 2015

Publication title -

folia histochemica et cytobiologica

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.384

H-Index - 40

eISSN - 1897-5631

pISSN - 0239-8508

DOI - 10.5603/fhc.a2015.0017

Subject(s) - chromosomal translocation , robertsonian translocation , fish <actinopterygii> , biology , genetics , preimplantation genetic diagnosis , karyotype , chromosome , embryo , fishery , gene

Carriers of reciprocal (RCP) and Robertsonian (RT) translocations are known to be at risk for reproductive difficulties. Preimplantation genetic diagnosis (PGD) is one of the options these carriers have to try to fulfill their desire to have a child. The FISH technique is one of the best method to detect RCPs, and, together with the Next Generation Sequencing, to diagnose RTs. The aim of the present study was to assess the usefulness of the FISH method for rapid diagnosis of translocations in our center to improve the reproductive counseling.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research