Stem cells and skin regeneration | Zendy

Marzena Staniszewska | Zendy; Sylwia Słuczanowska-Głąbowska | Zendy; Justyna Drukała | Zendy

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Stem cells and skin regeneration

Author(s) -

Marzena Staniszewska,

Sylwia Słuczanowska-Głąbowska,

Justyna Drukała

Publication year - 2011

Publication title -

folia histochemica et cytobiologica

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.384

H-Index - 40

eISSN - 1897-5631

pISSN - 0239-8508

DOI - 10.5603/fhc.2011.0053

Subject(s) - stem cell , regeneration (biology) , hair follicle , regenerative medicine , microbiology and biotechnology , epidermis (zoology) , biology , adult stem cell , skin repair , medicine , cellular differentiation , anatomy , immunology , wound healing , biochemistry , gene

Stem cells represent a great hope for regenerative medicine. In adult life, stem cell deposits are kept in organ niches; the need for tissue or organ regeneration mobilizes stem cells via the SDF-1-CXCR4 regulation axis. Constant regeneration of the skin is achieved due to stem cell differentiation within the epidermis and the hair follicle; thus, skin may serve as an excellent source of stem cells. This is of paramount importance in the treatment of chronic skin wounds and burns.

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