Cathepsin A activity of a parietal thrombus of an abdominal aortic aneurysm | Zendy

M. Siergiejuk | Zendy; M Gacko | Zendy; A Worowska | Zendy

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Cathepsin A activity of a parietal thrombus of an abdominal aortic aneurysm

Author(s) -

M. Siergiejuk,

M Gacko,

A Worowska

Publication year - 2011

Publication title -

folia histochemica et cytobiologica

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.384

H-Index - 40

eISSN - 1897-5631

pISSN - 0239-8508

DOI - 10.5603/fhc.2011.0003

Subject(s) - thrombus , cathepsin , abdominal aortic aneurysm , aneurysm , cathepsin b , cathepsin d , medicine , cathepsin a , chemistry , pathology , biochemistry , enzyme , radiology

We evaluated the cathepsin A activity of a parietal thrombus of an abdominal aortic aneurysm. We compared this activity to that of a retracted blood clot homogenate. Cathepsin A of aneurysm parietal thrombus homogenate and blood clot homogenate showed the highest activity on Z-Phe-Ala. It was lower on Z-Phe-Phe, Z-Glu-Tyr, Z-Glu-Phe, Z-Gly-Phe, and the lowest activity was on Z-Gly-Ala. We conclude that cathepsin A's activity on a parietal thrombus of an aneurysm is much higher than blood clot cathepsin A activity.

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