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The co-application of hypoxic preconditioning and postconditioning abolishes their own protective effect on systolic function in human myocardium
Author(s) -
Tomasz Roleder,
Krzysztof S. Gołba,
Marcin Kunecki,
Marcin Malinowski,
Jolanta Biernat,
Grzegorz Smołka,
Marek Deja
Publication year - 2013
Publication title -
cardiology journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.573
H-Index - 33
eISSN - 1897-5593
pISSN - 1898-018X
DOI - 10.5603/cj.2013.0131
Subject(s) - cardioprotection , medicine , cardiology , hypoxia (environmental) , ischemic preconditioning , ischemia , oxygenation , contraction (grammar) , anesthesia , oxygen , chemistry , organic chemistry
Ischemic preconditioning (IPC) and postconditioning (POC) are well documented to trigger cardioprotection against ischemia/reperfusion (I/R) injury, but the effect oftheir both co-application remains unclear in human heart. The present study sought to assessthe co-application of IPC and POC on fragments of human myocardium in vitro.

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