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Improvement of ventricular function in systolic heart failure patients with oral L-citrulline supplementation
Author(s) -
Karla Balderas-Muñoz,
Lilia Castillo-Martı́nez,
Arturo OreaTejeda,
Óscar Infante,
Marcelo Utrera-Lagunas,
Raúl MartínezMemije,
Candace KeirnsDavis,
Bryan Becerra-Luna,
Gabriela Sánchez-Vidal
Publication year - 2012
Publication title -
cardiology journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.573
H-Index - 33
eISSN - 1897-5593
pISSN - 1898-018X
DOI - 10.5603/cj.2012.0113
Subject(s) - medicine , ejection fraction , heart failure , cardiology , citrulline , arginine , biochemistry , chemistry , amino acid
The utility of L-arginine and L-citrulline in treatment of arterial hypertension by increasing vascular oxide nitric availability has been demonstrated. Photoplethysmography, a simple and low-cost optical technique, makes it possible to assess vascular function and to detect changes in blood flow, pulse and swelling of the microvascular tissular space. The aim of the study was to evaluate the effect of L-citrulline supplementation on functional class, ejection fraction and peripheral blood flow in patients with systolic heart failure.

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