Ovulation Induction and Cesarean Delivery After Panhpopituitarism Secondary to Lymphocytic Hypophysitis

Background: Lymphocytic hypophysitis is an unusual autoimmune disease that causes partial or total hypopituitarism and often is associated with pregnancy. Only four spontaneous pregnancies have been reported after this disease. We report a case of ovulation induction in a woman with this antecedent as well as the course of the subsequent pregnancy and delivery. Case Report: Ovulation was induced with gonadotropins in a 31-year-old woman with panhypopituitarism secondary to lymphocytic hypophysitis, achieving an uncomplicated single intrauterine pregnancy. A term healthy infant was delivered by cesarean section under epidural anaesthesia. Puerperal evolution was normal. Conclusions: Ovulation induction response was similar to that in panhypopituitarism of any other cause. Lymphocytic hypophysitis antecedent did not adversely affect pregnancy outcome nor was pregnancy-related disease observed. Epidural anaesthesia was effective for cesarean delivery in this case.