Effect of Caffeine on Some Transferase Enzymes Activities | Zendy

Zyad Al-Qaisi | Zendy; Selma Abdul Rudha Abbass | Zendy; Amer Abdullah | Zendy

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Effect of Caffeine on Some Transferase Enzymes Activities

Author(s) -

Zyad Al-Qaisi,

Selma Abdul Rudha Abbass,

Amer Abdullah

Publication year - 2011

Publication title -

international journal of chemistry

Language(s) - English

Resource type - Journals

eISSN - 1916-9701

pISSN - 1916-9698

DOI - 10.5539/ijc.v3n2p140

Subject(s) - chemistry , caffeine , transferase , enzyme , alanine , biochemistry , alanine aminotransferase , inhibitory postsynaptic potential , glutamate receptor , pharmacology , amino acid , medicine , receptor

This study was designed to show the effects of caffeine on the activities of aspartate aminotransferase (AST), alanine amino transferase (ALT), gama glutamate transferase (?-GT) enzymes in the sera. Caffeine demonstrated activation on (AST) and (ALT) activities, inhibitory effects on the (?-GT) activity, and these effects increased with increasing the concentration of the compound. Kinetic properties of (AST) and (ALT) activities revealed (by caffeine) non-competitive type of activation, and of (?-GT) activity competitive inhibitors

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