Effects of Letrozole-HMG and Clomiphene-HMG on Incidence of Luteinized Unruptured Follicle Syndrome in Infertile Women Undergoing Induction Ovulation and Intrauterine Insemination: A Randomised Trial | Zendy

Azra Azmoodeh | Zendy; Mansoureh Pejman Manesh | Zendy; Firouzeh Akbari Asbagh | Zendy; Azizeh Ghaseminejad | Zendy; Zeinab Hamzehgardeshi | Zendy

Open Access

Effects of Letrozole-HMG and Clomiphene-HMG on Incidence of Luteinized Unruptured Follicle Syndrome in Infertile Women Undergoing Induction Ovulation and Intrauterine Insemination: A Randomised Trial

Author(s) -

Azra Azmoodeh,

Mansoureh Pejman Manesh,

Firouzeh Akbari Asbagh,

Azizeh Ghaseminejad,

Zeinab Hamzehgardeshi

Publication year - 2015

Publication title -

global journal of health science

Language(s) - English

Resource type - Journals

eISSN - 1916-9744

pISSN - 1916-9736

DOI - 10.5539/gjhs.v8n4p244

Subject(s) - letrozole , ovulation induction , medicine , ovulation , gynecology , infertility , gonadotropin , hmg coa reductase , ovarian hyperstimulation syndrome , randomized controlled trial , andrology , pregnancy , in vitro fertilisation , biology , hormone , aromatase , biochemistry , cancer , breast cancer , reductase , genetics , enzyme

Luteinized unruptured follicle (LUF) syndrome is considered a cause of ovulation failure and a subtle cause of infertility. Preovulatory injection of human chorionic gonadotropin (HCG) prevents or treats LUF syndrome, but it has also occurred after the induction of ovulation with clomiphene/HMG and HCG. This study was designed for evaluation and comparison of LUF incidence in eligible infertile women undergoing two stimulation protocols (clomiphene + HMG and letrozole + HMG) in addition to intrauterine insemination (IUI). Some related factors were compared between LUF and non-LUF cycles as secondary outcomes.

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