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Culture and Real-Time PCR Based Maternal Screening and Antibiotic Susceptibility for Group B Streptococcus: An Iranian Experience
Author(s) -
Gholamreza Goudarzi,
Masoumeh Ghafarzadeh,
Pegah Shakib,
Khatereh Anbari
Publication year - 2015
Publication title -
global journal of health science
Language(s) - English
Resource type - Journals
eISSN - 1916-9744
pISSN - 1916-9736
DOI - 10.5539/gjhs.v7n6p233
Subject(s) - penicillin , clindamycin , erythromycin , carriage , group b , medicine , streptococcus , antibiotics , microbiology and biotechnology , antibiotic resistance , vancomycin , vagina , amoxicillin , biology , bacteria , surgery , staphylococcus aureus , pathology , genetics
Vertical Transmission of group B streptococcus (GBS) from a vagina colonized mother to her infant upon rupture of membranes (ROM) or after the onset of labor can cause life-threatening infections in newborn. Although intrapartum antibiotic prophylaxis (IAP) can significantly decrease neonatal GBS diseases, this issue has potentiated the emergence of antibiotic resistance strains. Our study examined the colonization rate of GBS using real-time PCR and culture methods, and trends in antibiotic resistance of GBS isolates obtained from pregnant women in Khorramabad, Iran.

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