Isoniazid Induced Liver Injury; a Case Series and Review | Zendy

Ramatati Anusha | Zendy; Sharad Chand | Zendy; Varun Lal | Zendy; Devarapu Mary Sushmitha | Zendy; Dhypa Sahithi Reddy | Zendy; Siddha Tejaswini | Zendy; Savanthi Chitrahasini | Zendy

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Isoniazid Induced Liver Injury; a Case Series and Review

Author(s) -

Ramatati Anusha,

Sharad Chand,

Varun Lal,

Devarapu Mary Sushmitha,

Dhypa Sahithi Reddy,

Siddha Tejaswini,

Savanthi Chitrahasini

Publication year - 2018

Publication title -

journal of pharmacy practice and community medicine

Language(s) - English

Resource type - Journals

ISSN - 2455-3255

DOI - 10.5530/jppcm.2018.2.30

Subject(s) - isoniazid , liver injury , causality (physics) , drug , medicine , series (stratigraphy) , pharmacology , intensive care medicine , pathology , tuberculosis , biology , physics , quantum mechanics , paleontology

Isoniazid is one of the most common drugs inducing liver injury, identifying and quantification of risk related to the drug is the prime to prevent and treat its occurrence. This case series tried to demonstrate the risk of drug (Isoniazid) by using the various causality assessment scales (RUCAM/CIOMS and Narnajo Algorithm). The cases taken were all males and taking the medication which on course develops the hepatotoxicity. It might be used as the literature for further study in addition similar studies are need to be carried out to understand the risk factor of drug induced liver injury. Key words: Isoniazid, Antitubercular therapy, Drug-induced liver injury, Hepatotoxicity.

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