Effects of 6-Week Micronutrient Supplementation on Sperm Parameters and Pregnancy Outcomes in Males with Idiopathic Infertility Undergoing Fertility Interventions: A Pilot Cohort Study
Author(s) -
Choo Gim Sun,
Aw Lin Da,
Ooi Bee Sen,
Zamri Yusof,
HuanKeat Chan,
Kathirgamanathan Balanathan,
Murizah Mohd Zain
Publication year - 2017
Publication title -
journal of pharmacy practice and community medicine
Language(s) - English
Resource type - Journals
ISSN - 2455-3255
DOI - 10.5530/jppcm.2017.4.63
Subject(s) - fertility , micronutrient , medicine , sperm , infertility , pregnancy , gynecology , pregnancy rate , semen , cohort , semen analysis , obstetrics , psychological intervention , sperm motility , population , andrology , biology , environmental health , pathology , genetics , psychiatry
Objective: To evaluate the effectiveness of the consumption of Profortil®, a combination of eight micronutrients, on sperm count, sperm motility, and pregnancy outcomes following a fertility intervention among infertile males in Malaysia. Methods: A cohort study was undertaken at the Seberang Jaya Hospital and the Sultanah Bahiyah Hospital, Malaysia. A total of 90 infertile males were enrolled, 52 of which decided to take two capsules of Profortil® daily for a six-week period during 1st September and 30th November 2016. Those who decided not to consume Profortil® served as the control group (n=38). Semen analysis and an observation of pregnancy outcomes following the fertility interventions were conducted after 6 weeks. Results: Despite the consumption of Profortil®, both groups showed a significant increase in sperm count (p Key words: Micronutrient Supplementation, Sperm count, Oligospermia, Male infertility, Pregnancy outcome
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