Wound Healing Activity of Herbal Ointment Containing the Extracts of Hibiscus rosa-sinensis Flowers and Curcuma longa Rhizomes
Author(s) -
Fazlina Mustaffa,
Subramani Parasuraman,
Geethaa Sahgal
Publication year - 2021
Publication title -
free radicals and antioxidants
Language(s) - English
Resource type - Journals
ISSN - 2231-2536
DOI - 10.5530/fra.2020.2.15
Subject(s) - rhizome , curcuma , traditional medicine , hibiscus , angelica sinensis , wound healing , officinalis , medicine , biology , botany , traditional chinese medicine , surgery , alternative medicine , pathology
Objectives: To evaluate wound healing activity of herbal ointment containing the extracts of Hibiscus rosa-sinensis flowers and Curcuma longa rhizomes. Methodology: H. rosa-sinensis flowers and C. longa rhizomes were extracted using 95% ethanol. H. rosa-sinensis and Hibiscus rosa-sinensis ointment were prepared using paraffin wax, lanolin and petroleum jelly. Ointment formulation was applied once daily on the excision wound made on Sprague Dawley rats for 20 days. Results: On day 20, the treatment group showed a significant increase in wound contraction which was 93.52 ± 1.38% when compared to control (87.62 ± 1.48%). Conclusion: Herbal ointment exhibited significant wound healing activity in rat excision wound model.
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