Changes in serum paraoxonase activity, calcium and lipid profiles in pre-eclampsia, a priliminary study | Zendy

Figen Babacan | Zendy; Birgül Işık | Zendy; Banu Bingöl | Zendy

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Changes in serum paraoxonase activity, calcium and lipid profiles in pre-eclampsia, a priliminary study

Author(s) -

Figen Babacan,

Birgül Işık,

Banu Bingöl

Publication year - 2011

Publication title -

journal of turkish society of obstetric and gynecology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.41

H-Index - 9

eISSN - 1307-7007

pISSN - 1307-699X

DOI - 10.5505/tjod.2011.24540

Subject(s) - eclampsia , paraoxonase , calcium , chemistry , medicine , pregnancy , biochemistry , biology , enzyme , genetics

SUMMARY Objective: To investigate serum paraoxonase (PON1) activity, serum calcium, and lipid profiles in pre-eclampsia. Material and methods: Serum PON1 activity, calcium, and lipid profiles were measured in a cohort of 45 women with normal pregnancies (11 patients) and pre-eclampsia (34 patients). Results: Triglyceride, total cholesterol, and LDL cholesterol concentrations were significantly increased in women with pre-eclampsia, compared with women with normal pregnancies. Serum HDL cholesterol, PON1, and calcium levels in pre-eclamptic patients were significantly lower than those in healthy pregnant women. Conclusion: The significant decrease of PON1 activity in pre-eclampsia is related to lipid profiles and calcium.

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