The relevance of serum levels of long chain omega-3 polyunsaturated fatty acids and prostate cancer risk: A Meta-analysis | Zendy

Michael Chua | Zendy; Maria Christina D. Sio | Zendy; Mishell C. Sorongon | Zendy; María Luisa González-Morales | Zendy

Open Access

The relevance of serum levels of long chain omega-3 polyunsaturated fatty acids and prostate cancer risk: A Meta-analysis

Author(s) -

Michael Chua,

Maria Christina D. Sio,

Mishell C. Sorongon,

María Luisa González-Morales

Publication year - 2013

Publication title -

canadian urological association journal

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.477

H-Index - 38

eISSN - 1920-1214

pISSN - 1911-6470

DOI - 10.5489/cuaj.1056

Subject(s) - prostate cancer , docosahexaenoic acid , polyunsaturated fatty acid , medicine , confidence interval , prostate , meta analysis , incidence (geometry) , relative risk , oncology , epidemiology , fish oil , cancer , physiology , gastroenterology , fatty acid , biology , biochemistry , fish <actinopterygii> , physics , fishery , optics

Our objective was to systematically analyze the evidence for an association between serum level long chain omega-3 polyunsaturated fatty acid (n-3 PUFA) and prostate cancer risk from human epidemiological studies. STUDY PROCEDURES: We searched biomedical literature databases up to November 2011 and included epidemiological studies with description of long chain n-3 PUFA and incidence of prostate cancer in humans. Critical appraisal was done by two independent reviewers. Data were pooled using the general variance-based method with random-effects model; effect estimates were expressed as risk ratio with 95% confidence interval (CI). Heterogeneity was assessed by Chi(2) and quantified by I(2), publication bias was also determined.

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