Open AccessAssay of In Vivo Chromium with a Hollow-fiber Dialysis Sensor
Author(s) -
Suw-Young Ly,
Hai-Soo Yoo,
Minki Jung,
Kwanghee Ko,
Byung-Jin Kim,
Ki-Chul Lee,
Byung Min Choi
Publication year - 2010
Publication title -
toxicological research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.872
H-Index - 30
eISSN - 2234-2753
pISSN - 1976-8257
DOI - 10.5487/tr.2010.26.3.233
Subject(s) - dialysis , in vivo , fiber , chromium , biomedical engineering , engineering , chemistry , materials science , medicine , metallurgy , biology , microbiology and biotechnology , composite material
The analytical in vivo chromium ion was searched for using a voltammetric hollow-fiber dialysis sensor via square wave stripping voltammetry (SW) , cyclic voltammetry (CV) , and chronoamperometry. Under optimum parameters, the analytical results indicated linear working ranges of 50~400 mg/l CV and 10~80 μg/l SW within a 30-sec accumulation time. The analytical detection limit (S/N) was 6.0 μg/l. The developed method can be applied to in vivo tissues and in ex vivo toxicity assay, as well as to other materials that require chromium analysis.
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