COVID-19: an update on diagnostic and therapeutic approaches | Zendy

Mahalaxmi Iyer | Zendy; Kaavya Jayaramayya | Zendy; Mohana Devi Subramaniam | Zendy; Soo Bin Lee | Zendy; Ahmed Abdal Dayem | Zendy; SsangGoo Cho | Zendy; Balachandar Vellingiri | Zendy

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COVID-19: an update on diagnostic and therapeutic approaches

Author(s) -

Mahalaxmi Iyer,

Kaavya Jayaramayya,

Mohana Devi Subramaniam,

Soo Bin Lee,

Ahmed Abdal Dayem,

SsangGoo Cho,

Balachandar Vellingiri

Publication year - 2020

Publication title -

bmb reports

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.511

H-Index - 77

eISSN - 1976-670X

pISSN - 1976-6696

DOI - 10.5483/bmbrep.2020.53.4.080

Subject(s) - pandemic , repurposing , covid-19 , medicine , intensive care medicine , hydroxychloroquine , coronavirus , disease , virology , infectious disease (medical specialty) , pathology , biology , ecology

The unexpected pandemic set off by the novel coronavirus 2019 (COVID-19) has caused severe panic among people worldwide. COVID-19 has created havoc, and scientists and physicians are urged to test the efficiency and safety of drugs used to treat this disease. In such a pandemic situation, various steps have been taken by the government to control and prevent the Severe Acute Respiratory Syndrome coronavirus 2 (SARS-CoV-2). This pandemic situation has forced scientists to rework strategies to combat infectious diseases through drugs, treatment, and control measures. COVID-19 treatment requires both limiting viral multiplication and neutralizing tissue damage induced by an inappropriate immune reaction. Currently, various diagnostic kits to test for COVID-19 are available, and repurposing therapeutics for COVID-19 has shown to be clinically effective. As the global demand for diagnostics and therapeutics continues to rise, it is essential to rapidly develop various algorithms to successfully identify and contain the virus. This review discusses the updates on specimens/samples, recent efficient diagnostics, and therapeutic approaches to control the disease and repurposed drugs mainly focusing on chloroquine/hydroxychloroquine and convalescent plasma (CP). More research is required for further understanding of the influence of diagnostics and therapeutic approaches to develop vaccines and drugs for COVID-19.

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